As the Cannabis market expands for medical and recreational use, so does the requirement for standardized quality control within the industry. With regards to Cannabis quality control there are many points to consider, from moisture content to pesticide use.
Moisture Content – Cannabis flower moisture content should be tested and controlled to: minimize the potential risk of mold formation; control microbiological levels; ensure proper drying, curing and storage conditions; and support product shelf-life. Some manufacturing processes for marijuana quality assurance plan also demand a certain water content within the starting material.
Terpenoids and Cannabinoids Analysis
The degree of terpenoids and cannabinoids inside the starting material determines the most suitable industrial processing method and which final cannabis product will likely be manufactured. This analysis is usually completed using LC-MS (Liquid Chromatography Mass Spectrometry) or GC (Gas Chromatography). LC-MS and GC require a flow of inert gas like hydrogen or nitrogen, each of which can be easily supplied by way of a gas generator. Uncover more regarding the Peak Scientific range of gas generators for GC & LC-MS here.
Pesticides and Herbicides – Similar to other agricultural crops and products meant for human consumption, Cannabis plants needs to be tested for herbicides and pesticides. Detecting pesticides and herbicides can be difficult due to the complexity of cannabis material. GCMS (Gas Chromatography Mass Spectrometry) is normally used for this function.
Microbiological Screening – Medical Cannabis is often used for HIV and cancer patients where the patient’s immunity mechanism has been compromised. Therefore, high microbial levels or pathogenic micro-organisms might be life threatening. It is crucial then that several Mycotoxins and fungus types should be detected included in cannabis quality control and release specifications.
Residual Solvents – Where solvents happen to be used as an element of Cannabis product processing, solvent residuals inside the final products should be tested to ensure that they meet the accepted criteria. The FDA has published zvqtob criteria for residual solvents in APIs for pharmaceutical use.
Chemical Toxins – Like many other plants, Cannabis draws metals from your earth. It really is therfore essential to test for Mercury, Lead, Arsen and Cadmium.
Cannabinoid Concentration – Concentration ranges for cannabinoids such as THC,THCa, CBD, CBDa, CBN, CBC, CBG should match the ranges specified on the product label, based upon product usage purpose, patient’s medical problem, age etc. Cannabinoid concentrations can be tested using LC-MS (Liquid Chromatography Mass Spectrometry) and HPLC (Good Performance Liquid Chromatography) . You will find a wide range of Peak Scientific nitrogen gas generators designed especially for LC-MS, available here.
Terpene Concentration – Terpenes increase cannabinoids’ therapeutic effects and are known to get their own health and fitness benefits, additionally they bring about Cannabis taste and aroma. They may be detected using GC.
Taking the above into consideration, it is actually clear that there exists a necessity for standarized procedures for all the Cannabis analysis and testing process so that you can guarantee safe use. The safest method to supply cannabis testing laboratories with gas for their LC-MS and GC is by gas generators, which usually do not present the health and safety risks connected with gas cylinders.